I'll be in San Diego and San Francisco next week as well. From the 20th to the 27th. Specifically Encinitas down South Cal and then Near Union in San Fran. I also heard that Alcatraz has been closed, but I remember we used to take a helicopter to the Island...it's been years, however.
I must say, I love San Francisco for the architecture mostly...but being from New Orleans, I can't say the food is as great as some have posted. Don't get me wrong, they put a lot of effort and money into creating a great atmosphere, but I've had better seafood in little hole in the wall restaurants here. However, one of my favorites is in the Mission called Ti couz (a little French crepe restaurant) 16th Street, (At the corner of Valencia Street), Quite good.
So, yes....go to the Warf...hit Ghirardelli Square...check out SFMOMA...you'll enjoy it.