Was just there a few months ago.
Napa Valley if you have the time; I love touring Stag's Leap Wine Cellars
Restaurant there called "Town Hall" is awesome; fun bar is Tres Agaves for tequela. Ate at one or two other top ones, but Town Hall was my favorite.
BE SURE to go to the farmer's market at the ferry building. Great view of bridge, fun shopping, etc.
If you have a woman w/ you she will want to shop @ union square (sak's, etc) Also many good watch stores there (Torneau, Cartier, Montblanc, etc).
China town was mainly just junk stores, but we weren't there long. Little italy is awesome, be sure to get pizza, canolli (sp?), etc
PM me if you have any questions; I'm sure there are residents here as well. GREAT vacation city.