Just my .02 here. I think this design would be better served on the older 36mm size. That way it also works as a Unisex watch. My wife would love that watch in the older smaller size. (The watch above does have some feminine-esq wear-ability qualities.)
I have also seen these in person and share RobbieG's feelings.
I think the leap from 36 to 41 is too much. As far as the 41's go, that 1mm does make a difference. 40mm ok, 39mm perhaps optimal??? Still refined, and elegant enough under a dress shirt. These 41's scream LOOK AT ME!
Like the new sub and deepsea, again in my opinion, I think their proportions are 'off'. If you are a big guy, I am sure they work great. I get the sense that these went onto the drawing board when the big oversized watch craze was fashionable. Now that understated is coming back, Rolex was perhaps too late to the market.
Final though, I saw a woman wearing a 41mm white face Milgauss-- LOOKED HORRIBLE on her. Way out of proportion and too loud. Conversely, I still like the look of a 40mm Sub (Cameron Diaz), or 40mm PAM (Heidi Klum) on a Women, but the new Rolex's not so much.
YMMV,